During a physical examination, the doctor may find swollen lymph nodes in the front and back of your neck, as well as swollen tonsils with a whitish-yellow covering.

The doctor might also feel a swollen liver or swollen spleen when pushing on your belly. There may be a skin rash visible for the doctor to see.

Blood work often reveals a higher-than-normal white blood cell count and unusual-looking white blood cells called atypical lymphocytes, which are seen when blood is examined under a microscope. Atypical lymphocytes and abnormal liver function tests are a hallmark sign of the disease.
A mono-spot test will be positive for infectious mononucleosis.A special test called an antibody titer can help your doctor distinguish a current EBV infection from one that occurred in the past.

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